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A new study found that male mice given high doses of antioxidant supplements like NAC fathered offspring with notable facial and skull abnormalities. Researchers link the effect to altered sperm DNA, even though the fathers appeared completely healthy. The findings raise concerns about supplements widely considered harmless or beneficial.

A new study reveals that high doses of antioxidants—often seen as harmless or beneficial—may actually impact future generations. Male mice given common supplements like NAC produced offspring with subtle but significant facial and skull changes. Researchers believe this is tied to altered sperm DNA, even though the fathers showed no outward health issues.