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In modern times we tend to think of lithium as powering smartphones and cars, yet its historical fame comes from its role as a mood stabilizer.

Lithium was first used as a treatment for bipolar disorder in 1949. Yet despite decades of research and drug development, this simple medication remains the gold standard for treating one of the most complex psychiatric conditions. But why?

According to Becci Strawbridge , a senior lecturer in psychological medicine at King's College London, lithium's simplicity could be what helps it cut through the complexity of bipolar disorder, a lifelong disorder that affects about 36 million people worldwide .

Clinically, bipolar disorder is defined as a mood disorder characterized by specific, lasting changes to a person's mood and energy levels. Depending on the type of bipolar disorder , individuals can experience manic, hypomanic and depressive episodes — either individually, or in sequence.

However, "experiencing mania itself is sufficient to have a diagnosis of bipolar [disorder]," said Dr. David Cousins , a clinical senior lecturer and honorary consultant psychiatrist at Newcastle University in the U.K. "It's probably easiest to think of that as the opposite of depression — people become elevated in mood, extremely energized, driven, motivated, and engage in hedonistic behavior with lots of risk taking," he said. "It's a highly detrimental, highly damaging, highly disruptive state."

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Treating an illness that operates at such extremes is a difficult balance to strike, with any intervention to treat one emotional state needing to factor in how it could impact the other. "For example, if you gave somebody antidepressants without an antimanic drug, you might either trigger mania or destabilize the illness," Cousins explained.

A combination of antidepressants, antipsychotics, and mood-stabilizing anticonvulsants are often prescribed in combination to juggle these highly variable symptoms. "There are really very few medications that have an overall effect against both poles," Strawbridge said. Once stabilized, the challenge then becomes preventing relapse back into this destructive cycle.

Lithium, by contrast, does not suffer from these limitations, Strawbridge added.

"It's often considered the gold standard for bipolar disorder; it's helpful for the depression and for the mania, but its main benefit overall is in preventing relapse, so stopping either of those two types of episodes from coming back."

Psychiatrists usually prescribe lithium as either lithium carbonate tablets or a lithium citrate liquid, both of which dissociate inside the body into lithium ions and their corresponding counterion (either carbonate or citrate). This simple active form is part of what gives lithium its powerful, broad-ranging mood-stabilizing effect, Strawbridge said.

"Because lithium is quite a simple ion, it's able to disguise itself as sodium, and that means it can slip inside of brain cells, whereas most medications act on the surface of cells," she explained.

Simple lithium drugs are still the gold standard for treating bipolar disorder. (Image credit: Ray Geiger via Getty Images) Lithium's simple form enables it to spread throughout the brain and rest of the body. Once inside, it interacts with many cellular processes, but doctors still don't really understand the underlying mechanism behind its beneficial effects.

"We know that the monoamine system and the neurotransmitters in the brain that are involved in reward emotions and cognition are disrupted," Victoria Wing , a clinical lecturer at the National Institute for Health and Care Research at Newcastle University and CNTW NHS Foundation Trust, told Live Science. Included in this disruption is the regulation of crucial mood molecules, such as dopamine and serotonin, which may be underactive or overactive depending on the nature of the bipolar episode.

The same small lithium ion also blocks an enzyme called glycogen synthase kinase 3. This enzyme has wide-ranging downstream effects, such as controlling gene activity, regulating the body's circadian rhythms and managing inflammation and cell survival.

"Lithium can also help with autophagy, which is the clearance of debris and toxins in cells, and it has antioxidant effects and boosts mitochondrial function, which are important for cell energy processes," Wing said.

However, despite its manifold therapeutic benefits, lithium does have some drawbacks. While around one-third of people experience profound benefits from the drug, another close third only experience intermediate effects, and the final rough third don't respond at all.

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This means it's vital to identify which patients respond well to the drug as early as possible, especially because the cyclic nature of the condition means it can take years to ascertain whether lithium is effective in preventing relapses in the long-term, said Cousins. The drug also has a narrow therapeutic window, which means it has a small margin of safety between doses that are high enough to be effective and those that are toxic to the kidneys and thyroid. Some patients who undergo lithium treatment also report having to urinate more frequently or experiencing slight tremors .

As with any medication, some side effects are unavoidable. The alternatives to lithium also carry their own risks. But if carefully and correctly managed, lithium medications can have a transformative impact for patients.

"I've met a lot of patients through patient involvement groups that have told me how effective and lifesaving lithium has been for them," Wing said. "We know it works, but can we fine-tune the use even better so more people can benefit from it?"

This article is for informational purposes only and is not meant to offer medical advice.

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NASA is moving forward with designing a new space telescope that can see even deeper into the infrared universe than the James Webb Space Telescope (JWST) can.

The new mission, called PRIMA (Probe far-Infrared Mission for Astrophysics), is continuing its development to Phase B — the preliminary design and tech phase — according to a NASA statement . Managers will review the mission's progress before officially beginning the telescope's journey to launch; if all goes to plan, PRIMA will embark on a five-year mission no earlier than 2033.

PRIMA's objective is to use a 5.9-foot [1.8 meters] telescope to examine the cosmos in the far-infrared, in a different set of wavelengths than the more famous JWST, which launched in 2021. (Other telescopes, such as Hubble and the newly launched Nancy Grace Roman Space Telescope , can also see some infrared wavelengths, but JWST was specifically designed to detect near- and mid-infrared light .) PRIMA's mission focus will be to uncover more information about exoplanet origins, galaxy growth and black hole evolution.

"The key science questions that PRIMA aims to address in relation to planet formation are to quantify the role of water in driving planet formation, [and to] determine the total gas masses and carbon and oxygen abundances in disks to reveal where exoplanets form," Meredith MacGregor , an associate professor of physics and astronomy at Johns Hopkins University who studies how planetary systems form, told Live Science in an email.

"We can't actually address these science questions with JWST," MacGregor added, "because the spectral lines that are required are only in the far-infrared — longer wavelengths than JWST is sensitive to."

The University of Maryland (UMD) and Caltech, which helped develop the mission, each issued statements about the upcoming work.

"I'm most excited about the things I don't yet know," Alberto Bolatto , an observational astronomer at UMD and a co-investigator who leads galaxy evolution research for PRIMA, said in a statement . "I am elated to be part of the future of astronomy — to produce an instrument that is going to be an enormous tool for the astronomy community to move humanity's knowledge forward."

"I am particularly excited about how PRIMA will help us discover and understand the role of powerful molecular outflows in galaxies over cosmic time, and how they shape star formation and the growth of supermassive black holes in the centers of galaxies," Lee Armus , a staff scientist at Caltech and the PRIMA co-investigator and science operations lead, said in a separate statement .

Dawn of the Probe Explorers

PRIMA has a project cost cap of $1.2 billion, excluding launch and other nonproject expenses; for comparison, JWST cost $10 billion at launch in 2021, not accounting for inflation or launch expenses.

PRIMA is also the first in a new class of spacecraft that NASA is calling Probe Explorers, which are meant to sit somewhere in between flagship, JWST-style missions and smaller agency efforts. Probe Explorers are a part of the decades-old Explorers Program that began with the Explorer 1 launch in 1958 and followed with more than 100 missions. Explorers perform "a wide variety of research and scientific exploration programs for Earth studies, space weather, the solar system, and the universe," according to the agency.

Explorer 1 (seen here) was the first satellite launched by the U.S. when it lifted off January 31, 1958. (Image credit: NASA/Joel Kowsky) The Probe Explorers were implemented after a recommendation from astrophysicists through the 2020 Decadal Survey, which is a consensus report issued by the National Academies of Sciences, Engineering, and Medicine on behalf of the community. NASA funded two concepts at $5 million apiece in 2024 and considered both PRIMA and the Advanced X-ray Imaging Satellite before announcing the decision to proceed with PRIMA this week.

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"NASA selected PRIMA for development after detailed evaluation of concept studies for Probe Explorer missions, based on their scientific merit in alignment with the Decadal Survey's recommendations, feasibility of their development plans on cost and schedule, and use of technologies that could support the development of future large missions," the agency stated Wednesday (Sept. 23).

Should the mission fly as hoped, NASA's Jet Propulsion Laboratory will manage PRIMA, with contributions from numerous other NASA centers and international agencies.

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MAUI, Hawaii — Engineers have built a first-of-its-kind artificial intelligence (AI) audio chip for wearable devices that they say will let users engage with AI assistants without needing to maintain a smartphone connection. Devices with the new chip will also harvest audio ‪—‬ and even video ‪—‬ data from the world around you to better serve these virtual agents.

The new chip, called Snapdragon Sound Elite Gen 2, will pave the way for new features that are currently unavailable directly in portable devices such as headphones, smart glasses and speakers. Qualcomm representatives announced the new chip at the company's annual Snapdragon Summit, hosted here Sept. 21-24.

Unlike current earbuds, devices with the new chip will be able to host apps right on the memory of the devices themselves, without relying on a continuous smartphone connection, as well as sync with cloud-based services like ChatGPT when connected to Wi-Fi. In practice, the chip will enable users to make vocal queries and requests, with an AI model taking actions such as setting up entries in an online calendar or making online purchases. Unlike existing devices that can perform similar functions, this would be possible without a smartphone connection.

Beyond earbuds, company representatives want to integrate the chip into other "hearables," such as over-ear headphones, open-ear audio devices, audio glasses, camera buds (headphones that use tiny built-in cameras) and hearing devices, as well as "future personal AI wearables," like pendants or clips.

What features will the chip enable, and how does it work?

For users who wish to connect hearables to a smartphone or computer (to interact with a visual user interface, for example), the new chip uses a specialized component within the platform to establish connections over micropower Wi-Fi channels alongside Bluetooth. This technology harnesses architectural improvements at the chip level to consume much less power than standard Wi-Fi connections — but at the expense of higher latency and lower peak speeds. For audio devices, however, using Wi-Fi rather than Bluetooth generally improves playback quality, given that Bluetooth compresses data during transmission, Qualcomm representatives said.

Adaptive and selective active noise cancellation also means users can filter out audio on command. For example, it allows listeners to hear key sounds, such as emergency sirens, while walking through a city or highlight people's voices during a conversation, while blocking out everything else. This noise cancellation is achieved through standard machine learning algorithms, rather than transformer-based large language models that power AI systems like ChatGPT.

Devices could also allow lossless audio streaming — a high-quality audio standard that's usually available only if you subscribe to premium streaming services, like Spotify or Tidal — thanks to another built-in subsystem.

The new chip enables devices to feature an AI assistant that can engage in two-way conversations. (Image credit: Keumars Afifi-Sabet/Live Science) Qualcomm representatives also highlighted the chip's "always-on intelligence," in which an on-device eNPU AI accelerator component powers virtual assistants, transcription and translation, as well as the building of "contextual awareness." With contextual awareness, the system would constantly monitor the user's environment to harvest data to add to a personal profile, which representatives say helps it answer future queries.

Although the system is audio-centric, it's also built to interface with hardware that includes sensors and cameras — like earbuds with built-in lenses that passively capture footage of a wearer as they go about their daily lives. This forms part of the data harvesting to build contextual awareness for the agentic AI systems people can access. Qualcomm representatives attempted to assuage privacy concerns by saying camera lenses on future earbuds would be low resolution and wouldn't identify specific individuals due to an AI mask that automatically obfuscates them.

There's no information yet about the likely impact of these features on battery life compared with conventional non-AI devices. But Qualcomm representatives noted that device makers will no longer need to choose between audio quality, AI features and battery life. That said, Andrew Laister, staff product manager at Qualcomm, added in a media Q&A session that there's likely to be an impact on how a user experiences battery drain. That's because, unlike conventional earbuds that are used sporadically for calls and music playback, these new devices are designed to be used continuously.

How does Qualcomm's new AI chip compare with similar technologies?

AI-enabled headphones already exist in some capacity. For example, manufacturer Viaim launched its Rise and RecDot devices this year. These are designed to record, transcribe, translate and summarize conversations, although details on the chips powering them are not publicly available. Apple's AirPods, for example, let users tap into the Siri AI system, but they require a continuous iPhone connection to perform complex tasks.

Devising smart audio features and getting them to work in real devices have also been at the heart of several recent research projects. For example, in 2024, University of Washington scientists embedded a computing system into off-the-shelf earbuds to zero in on individuals speaking in noisy environments while blocking all background noise.

The previous year, the research team put a deep learning system into headphones so wearers could use voice commands to engage with a selective active noise cancellation system, choosing which sounds to hear and which ones to block out.

Other companies have explored building new kinds of digital audio platforms for headphones. Three years ago, xMEMS unveiled Cypress , an audio chip that generates ultrasonic sound using the "piezoelectric effect," in which a material moves when a current is applied to it. Although the chip entered "mass-production readiness" in September 2025, consumer devices fitted with the platform have yet to be announced.

Apple also may be working on a similar technology. This could manifest as AirPods with built-in cameras that will perform similar data harvesting as users go about their day-to-day lives, according to Bloomberg Managing Editor Mark Gurman .

It's like the first smartphone moment with the Play Store.

Andrew Laister, staff product manager at Qualcomm.

Qualcomm's new chip is a spiritual successor to the 3-year-old Snapdragon S7 Gen 1 system, which featured in devices such as the Xiaomi Buds 5 Pro series. The previous chip also used AI for conventional active noise cancellation, audio customization and lossless audio streaming while connecting to devices via micropower Wi-Fi.

However, the new chip has twice the AI power, completing 128 billion operations per second, compared with the previous one's 64 billion operations per second. It also uses 40% less power and is 30% smaller.

A crucial aspect of the new system is its capacity to store apps on the device itself in the chip's onboard memory. Because the device will have its own IP address, it can communicate with servers using the https protocol, without needing to go through another phone or computer.

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Laister told journalists in the Q&A session that the company is currently scoping out whether the device could run two apps in RAM (short-term memory) at once — an AI agent and an audio streaming platform, for example — while keeping the rest in flash memory (long-term storage). He added they had to overcome a communication hurdle with micropower Wi-Fi foron the launch of the previous chip (specifically, that its power consumption is on a par with Bluetooth's). Now, he said the communication hurdle is actually being able to run apps on the device.

"It's like the first smartphone moment with the Play Store, but in this sense, that app store for your earbuds is currently owned by the device maker," he added. "They will be the guys that will choose which apps they will pre-bundle, and then we'll go from there."

No details were available on when the system is likely to be found in devices, but representatives said Qualcomm is working with other companies, including HP and Bose, to explore headphones and speakers that feature the chipset.

Live Science was invited to attend Snapdragon Summit 2026 courtesy of Qualcomm, with the company covering travel and accommodation.

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Fusion-powered space travel has long held the promise of rapid trips across the solar system: Mars in weeks, Saturn in months, Pluto in years.

For decades, such possibilities have remained theoretical, like something plucked out of a science fiction novel. But several companies are now working to build practical nuclear fusion propulsion engines, with significant milestones being hit.

Pulsar Fusion, a U.K.-based startup, hopes to launch a demonstration mission to space in 2027, while Princeton University and Helicity Space in the U.S. are continuing their own work on fusion drives.

Richard Dinan, the CEO of Pulsar Fusion, displays the Sunbird spacecraft at the company's facility in Bletchley, England. (Image credit: Pulsar Fusion) If any of these efforts prove successful, missions across the solar system for robots and humans could be unlocked like never before, turning us into a true spacefaring species.

"If we continue on the current trajectory, everything we know about space travel is going to change within a decade," Stephane Lintner , CEO and co-founder of Helicity Space, told Live Science.

But is it too good to be true? Can the dream of nuclear fusion propulsion ever be fully realized, or will it remain a sketchbook fantasy? After decades of dreaming, we might be on the cusp of finding out.

Fusion power

Nuclear fusion is a process whereby two atoms combine, or fuse, to form a heavier one, releasing excess energy in the form of light and heat. The best-known type of fusion is the process that occurs inside the sun at up to 27 million degrees Fahrenheit (15 million degrees Celsius), where atoms of hydrogen fuse to form helium.

If this process could be replicated on Earth, it would provide us with huge amounts of energy. "The holy grail is free energy for everyone," Lintner said. Entire cities and countries would be transformed, bringing about a new age of clean and abundant power.

Many experiments and tests have been performed , and large fusion experiments, like the International Thermonuclear Experimental Reactor (ITER) in France, are under construction. However, commercially viable fusion reactors have yet to be built. One of the main problems is keeping the turbulent, superhot plasma required for fusion confined and at the right temperature. The record is currently 22 minutes.

If you take the same concept and put it in space, you suddenly have a means to power a spacecraft. What's more, the same problems with sustaining the plasma don't arise. Instead, the plasma can be fired out of the spacecraft, providing a steady thrust that can be used to accelerate a spacecraft to enormous speeds in the frictionless vacuum of space.

"Fusion propulsion in some ways is harder, and in some ways is easier, than terrestrial energy production," Bhuvana Srinivasan , a professor of aeronautics and astronautics at the University of Washington, told Live Science.

A fusion-powered spacecraft could be accelerated to hundreds ‪—‬ or even thousands ‪—‬ of miles per second through this method, multiple times faster than any spacecraft in history . In the most optimistic scenario, such a spacecraft could reach significant fractions of light speed , making interstellar travel a possibility.

There are tremendous challenges, of course. A space-based fusion reactor must be small enough to fit inside a spacecraft on a rocket. That's no easy feat, considering fusion reactors like ITER are the size of houses. You also need a way to create the immense heat required for fusion to occur, a source of fuel and propellant, and powerful magnets to keep the plasma from burning through the engine's walls.

Fusion propulsion in some ways is harder, and in some ways is easier, than terrestrial energy production.

Bhuvana Srinivasan, professor of aeronautics and astronautics at the University of Washington

Producing meaningful thrust requires staggering numbers of fusion reactions every second. A quintillion reactions would provide about 10 newtons of thrust ‪—‬ equivalent to the weight of a 1-liter bottle of water in your hand. But a fusion-powered engine would provide this thrust for months, rather than minutes for typical chemical propulsion, allowing large speeds to be reached eventually.

At first glance, this might sound nearly impossible, but some recent tests have shown it could be plausible

First plasma

In March, Pulsar Fusion demonstrated "first plasma" inside a nuclear fusion engine for the first time. In the test, which took place at the company's facility in Bletchley, one of Pulsar's Sunbird engines briefly transformed krypton gas into a plasma , demonstrating how the company might confine plasma within its exhaust system.

The demonstration showed "the plasma will sit in the system where you want it to sit," confined by an electromagnetic field, Richard Dinan , the company's CEO and founder, told Live Science. "The difficult work now is to be able to heat the plasma to temperatures nearer to fusion."

A display model of a Pulsar Sunbird engine, which briefly transformed krypton gas into a plasma in March. (Image credit: Pulsar Fusion.) Dinan founded Pulsar Fusion in 2011 with the goal of building a fusion-powered propulsion system. The company's plan is to fuse helium-3 and deuterium, a lighter form of helium and a heavier form of hydrogen, and use the energy produced to heat helium-4 and expel it as propellant to produce thrust. The amount of thrust that can be produced depends on "how good you are at diverting those particles out the back of the spacecraft," Dinan said. "And right now, nobody knows how efficient we can be."

Just a few hundred grams of deuterium and helium-3 fuel would be needed to sustain the fusion process on a trip to Mars, Dinan said, but he claims their rocket would need 10 to 20 metric tons (11 to 22 U.S. tons) of deuterium propellant to provide the thrust to reach the speeds they're hoping for.

If they can make it work, their plans are ambitious. The company imagines fleets of its Sunbird vehicles traversing the solar system, taking people and cargo to and from destinations at speeds of up to 329,000 mph (529,000 km/h) ‪—‬ about 10 times faster than the Voyager 1 spacecraft currently traveling outside the solar system.

At those speeds ‪—‬ which aren't reached instantly, as the spacecraft need months to accelerate and decelerate ‪—‬ travel time to Mars could be halved from the nine months it takes with conventional chemical propulsion. Weight could be freed up for equipment because fusion is more efficient and needs less fuel. Quicker missions to farther destinations, such as to Saturn's moon Titan or the metal-rich asteroid Psyche, would also be in reach.

"I think we will see fusion as a propulsion system pretty soon," Dinan said. "The demand is certainly there."

A billion degrees

Pulsar Fusion's method of propulsion is known as dual direct fusion, where the plasma from the process is directly used to provide thrust. Samuel Cohen , a physics professor at Princeton University, is working on a similar concept, the Direct Fusion Drive , as part of a project called Starfire .

Cohen and his team have been investigating this concept for more than 20 years . Their idea is to fuse deuterium and helium-3, which is rare on Earth but abundant on the moon. His team has built a prototype fusion thruster at Princeton with plasma that reaches 18 million F (10 million C).

"It's a start, but you've got to get to a billion degrees" Celsius for deuterium and helium-3 fusion to occur, Cohen told Live Science. There are a few promising approaches to reaching those temperatures, including squishing the plasma or heating it up with radio or neutron beams.

Using their current plasma, Cohen claims the team has demonstrated a small amount of thrust ‪—‬ a few milligrams, or a few hundred-thousandths of a newton. Now, they hope to get more funding to take their concept further. "We need a few million dollars to start things off," Cohen said.

With enough support, Cohen said, they could have a working fusion propulsion system in 10 to 20 years. Meanwhile, Pulsar Fusion, which has received support from the European Space Agency and the U.K. Atomic Energy Authority , hopes to perform a demonstration of its thrusters in orbit by 2027.

Helicity Space is targeting a launch of its fusion propulsion system in the 2030s. The company, which raised $5 million in 2023 , is developing the Helicity Drive , which relies on pulses of plasma, rather than continuous fusion, to provide thrust.

An artist's illustration of Helicity Space's Helicity Drive. (Image credit: NASA/Ryan Weed) "If you get a reaction every few seconds, that's an amazing science experiment on Earth, but you can't do anything with it," Lintner said. "In space, you have the most advanced electric propulsion drive ever built. You change the game for propulsion."

Lintner said the company is aiming "for fusion temperatures very, very soon," and is then "planning on flying a first prototype within three years." By the 2030s, Lintner hopes to reach net gain in its fusion engines ‪—‬ producing more energy than is put in ‪—‬ to have a true fusion drive ready for use in space.

Going interstellar

But not everyone is convinced that fusion drives will propel us through the solar system. John Slough , who is working on his own fusion rocket design called the Fusion Driven Rocket (FDR) , said he is wary of "false promises" in the field. He noted that much of the underlying physics around fusion propulsion remains extremely difficult.

"It still relies on scientific discovery for us to push it," Srinivasan said. "We need to figure out, how do we keep this fuel stable? Have we sorted a lot of the engineering and scientific challenges? It's not going to happen next year."

Remaining challenges include not only keeping the plasma stable, but also developing walls that can sufficiently contain the plasma, and shrinking the fusion system to fit inside a spacecraft, she added.

Other forms of nuclear propulsion might be more promising. NASA is developing SR-1 Freedom , a spacecraft powered by nuclear fission, not fusion. The goal for the spacecraft, announced in March, is to launch to Mars by December 2028, where three small robotic helicopters would be sent to explore the surface. The fission reactor would split uranium-235 to generate thrust.

The planned flight trajectory of the SR-1 Freedom craft. (Image credit: NASA) "SR-1 Freedom will pave the way for space nuclear hardware," Steven Sinacore , the Space Reactor-1 Freedom Program Director at NASA, told Live Science in response to questions via email. "To sustain a presence on the Moon, send crews to Mars, and explore the outer solar system, the nation needs power that works everywhere, independent of the sun, and fission is that power."

However, fission-based propulsion, while extremely useful, cannot match the speeds promised by fusion propulsion. That's because fusion systems magnetically confine the plasma, meaning much higher temperatures can be reached . Fission temperatures, by contrast, are limited by the materials of the reactor where the fission reactions take place.

If any of the proposed fusion concepts were to become a reality, however, the possibilities would be enormous. Last year, Elena Ancona , a flight dynamics engineer at the Polytechnic University of Bari in Italy, and her colleagues described how a direct fusion drive could enable a mission to Sedna , a remote icy dwarf planet far beyond Neptune. For that mission, time is of the essence.

An artist's illustration of Sedna. Named after the Inuit goddess of the sea, this dwarf planet has one of the most distant orbits in the solar system, stretching far beyond Pluto. (Image credit: CoreyFord via Getty Images) Exclusive to Live Science Pro

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The dwarf planet will reach its closest point to the sun in 2075 , and it will not be that close again for another 11,000 years. "If we want to make this mission, it's either now or in 11,000 years," Ancona said. With a traditional chemical spacecraft, a mission would need to be launched 30 years in advance. But with fusion propulsion, it could get to Sedna in just 10 years .

Many more destinations would be within reach if fusion propulsion were to become a reality. Perhaps even interstellar travel would be possible much further down the line. "People have known that fusion is the answer to deep-space travel since the 1960s," Lintner said. "It's only in the last decade that, commercially, people started to spend a lot of time on cracking the fusion code."

But there's a long way to go. "It's not for the faint of heart," Lintner said. But if fusion propulsion is ever going to happen, the next few years look as good a bet as any.

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Archaeologists have unearthed a monumental 2,700-year-old tomb at Vulci, an important ancient Etruscan town north of Rome. Despite repeated attempts by tomb robbers to loot this burial over the centuries, the tomb still contained a massive collection of grave goods, including weapons, gold and bronze plates, chariot parts, a rare pair of women's shoes, and a complete banquet set.

The burial, nicknamed the Tomb of the Stone Chamber, was excavated this summer, according to a translated statement from the Italian Superintendency of Archaeology, Fine Arts and Landscape for the Province of Viterbo and Southern Etruria (SABAP-VT-EM). But the discovery builds on work that French archaeologists carried out in the late 19th century.

In 1889, archaeologist Stéphane Gsell identified the circular enclosure of the Etruscan burial mound in the cemetery at Vulci. But while Gsell delineated what he thought was the perimeter of the grave, he never found the tomb itself because he ran out of time and money to dig further.

Now, archaeologists with the Return to Vulci project think they've finally found the burial chamber inside the "Gsell tumulus" — and it's much larger than they, and Gsell, expected.

"This is the burial. We are absolutely certain of it," Christian Mazet , an archaeologist at the British Museum and co-director of the project, told Etruscan Times . The discovery of weapons, parts of a chariot, gold objects and high-quality ceramics means "there is no doubt that this is a tomb of the very highest rank," he said.

The new excavation revealed the Tomb of the Stone Chamber, which dates to the seventh century B.C. Archaeologists uncovered the walls of the tomb's three burial chambers and found numerous artifacts preserved beneath the chambers' collapsed roofs, including jewelry, clothing and shoes.

In the side chambers of the tomb, archaeologists recovered much rarer items, according to the SABAP-VT-EM statement, such as a bronze tripod made on what is today the Greek island of Rhodes, just off Turkey's southwest coast. They also found a nearly complete banquet set, and some of the vessels were still in their original positions after spending centuries underground.

The Etruscan cemetery at Vulci is well known for its wealthy tombs, thousands of which were discovered in the 19th century. But although the Indigenous Etruscans ruled over central Italy for several centuries, their society began to decline in the fourth century B.C., owing to the rise of Roman civilization . Their language is only partly understood today, meaning most information about the Etruscans comes from archaeological sites such as Vulci.

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The Tomb of the Stone Chamber was built in Vulci's heyday. Gsell had estimated the size of the tumulus at around 102 feet (31 meters) in diameter, calling it a "new Cuccumella," referring to the largest Etruscan burial mound previously discovered at Vulci. (The giant Cuccumella tumulus had a diameter of roughly 230 feet, or 70 m.) According to Etruscan Times, the Return to Vulci project experts' initial calculations suggest that the Tomb of the Stone Chamber may have been similar in size to Cuccumella, ‪or perhaps even larger.

"Everything tells us that it is one of the most monumental at Vulci," Mazet told Etruscan Times.

The tomb and burial mound have been covered to preserve them, according to the SABAP-VT-EM statement, but research will continue in 2027.

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Rare fossils discovered in Japan more than 30 years ago are from a new species of armored dinosaur — one whose ancestors likely reached Asia by trekking across a land bridge, a new study finds.

The newly named dinosaur, a type of nodosaurid, is now one of just three species of its kind found in Asia to date. The scarcity of nodosaurids in Asia, and the fact that the newly described beast is similar anatomically to those from North America, hint that its species likely arose from a migration from North America to Asia via the Bering Land Bridge, an ancient strip of land that connected present-day Alaska and Russia, researchers reported in the February 2027 issue of the journal Cretaceous Research .

"It's super cool to see [the specimen] getting a new look and a new name," said Victoria Arbour , manager of research and collections at the Royal B.C. Museum in Canada. Arbour was not involved in the new work.

Nodosaurids are armored dinosaurs covered in bony plates. They are closely related to ankylosaurids, but they lack the heavy tail clubs ankylosaurids used to protect themselves from predators. Nodosaurid fossils have primarily been found in North America and Europe, though a few have been uncovered in Asia.

In the new study, a team of researchers revisited one such fossil specimen originally discovered in 1995 on Hokkaido, the northernmost main island of Japan. The scientists performed computed tomography (CT) scans of the fossils, which are somewhere between 93 million and 100 million years old, and include the back of the skull, part of the lower jaw, and several teeth and bony plates.

Ancestors of Nipponopelta yezoensis likely migrated along the North American coastline and across the Bering Land Bridge to present-day Japan, which was connected to mainland Asia at the time, a new study suggests. (Image credit: Masato Hattori) CT scanning enables researchers to make digital 3D models of specimens, and "lets you just get more information than you'd be able to have otherwise, because you can look inside without breaking [the fossil]," Arbour told Live Science.

Based on the CT scans and an anatomical analysis, the team determined that the fossils represented a new species of nodosaurid, which they dubbed Nipponopelta yezoensis . "Nippon" refers to Japan, and "pelta" means "shield" in Greek. "Yezo" is the traditional name for Hokkaido.

N. yezoensis is closely related to North American nodosaurids, the team found. The dino's ancestors may have migrated from North America to Asia via a land bridge in what is now the Bering Strait 100 million to 110 million years ago.

CT scans show where the recovered Nipponopelta yezoensis fossils would have been inside the animal's head. (Image credit: Oyabu et al 2026) Coastal dinosaur?

A separate team of scientists originally uncovered the N. yezoensis specimen in marine sediments — rocks that formed under ancient seas. Nodosaurids didn't live in the ocean, so the findings suggest that after the animal died, its corpse may have been swept out to sea along a river or estuary and eventually sank to the ocean floor.

Several other nodosaurid fossils have been found in similar marine deposits , suggesting the creatures lived along coastlines. That may have helped them migrate along the Bering Land Bridge and disperse by following the coast, study co-author Darla Zelenitsky , a dinosaur paleobiologist at the University of Calgary, told Live Science.

Nipponopelta yezoensis would have walked on four legs, eaten plants, and lived in a coastal region, researchers suggest. (Image credit: Genya Masukawa) But just because nodosaurids are most commonly found in coastal environments doesn't mean that they couldn't have lived further inland as well, said Jordan Mallon , a paleontologist at the Canadian Museum of Nature who was not involved in the research. Upland and mountainous regions tend to produce few fossils because erosion wears down rocks in these biomes, Mallon told Live Science. So it's possible nodosaurids lived there, even if there's no fossil record of these armored dinosaurs at these locations.

"The nature of the fossil record is that it's patchy and incomplete," Mallon said. "It's very hard to tell a comprehensive story when you've only got a few pages out of a phone book's worth of time."

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It's also not clear from the fossil record why so few nodosaurid species have been found in Asia compared with North America, Zelenitsky said. While several ankylosaurid species have been found further inland in Asia, few nodosaurid fossils have been unearthed on the continent.

"It could be the rock record, or just that [nodosaurids] weren't able to diversify as much in Asia," Zelenitsky said.

In future studies, "I hope that we find more of this animal," Mallon said. "It incites us to keep digging so that we can learn more about this animal and test some of our ideas about just what it is."

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In July 2025, a large, bright cosmic object visited from beyond our solar system. Only the third interstellar object ever discovered, the comet — named 3I/ATLAS — swooped through the inner solar system for about four months , briefly making it one of the biggest science celebrities in the world.

The interstellar object's fame stemmed in large part from controversial (and unsubstantiated) claims that it could be a source of intelligent alien technology , even though 3I/ATLAS behaved like a natural comet. However, according to the astronomers who are studying its mysteries in the data collected by dozens of telescopes and spacecraft, the ancient object may still have lessons to teach us about life in the cosmos.

3I/ATLAS is likely a preserved fragment of a planetesimal — a building block of a planet — from a distant system, Martin Cordiner , a researcher in astrochemistry and planetary science at NASA's Goddard Space Flight Center, told Live Science. Therefore, the comet's composition could offer clues to the prevalence of life's building blocks around distant stars. Some astronomers even hope this cosmic interloper will help constrain how likely life is elsewhere in our galaxy.

Blast from the past

Comets like 3I/ATLAS are important because scientists think they help "seed" planets with carbon-containing chemicals, Darryl Seligman , an assistant professor of astronomy at Michigan State University, told Live Science in an email. Some of these chemicals, like methanol, have simple structures. Others, like amino acids, are more complex. Together, these carbon-containing, or organic, compounds form the basis for biomolecules, like proteins and nucleic acids, that interact to produce life.

Samples returned from space rocks in our neighborhood strongly support the idea that they transported such molecules within the solar system. For instance, fragments from the solar system asteroid Bennu obtained during NASA's OSIRIS-REx mission contain all five nucleotide bases , the building blocks of nucleic acids. Matthew Belyakov , a postdoctoral researcher in planetary science at Caltech, noted that the Bennu samples also contained 14 of the 20 amino acids that form naturally on Earth.

3I/ATLAS, in its nearest close-up, taken by the Mars Reconnaissance Orbiter. Observations with space- and ground-based telescopes have found that the comet contains tons of organic molecules. But what does this mean for the prospect of life elsewhere in our galaxy? (Image credit: NASA/JPL-Caltech/University of Arizona) Inferences about such deliveries are possible only because the rocks are like time capsules: They emerge from the same swirling disk of gas and dust from which planets are born, and the chemical compositions of asteroids and comets don't change much after that. So, by studying space rocks that originate in other exoplanetary systems, "we can learn if they also contain the building blocks of life and could have helped to start life in exoplanetary systems," Seligman said.

Simulations suggest that comets that circle one planet before moving to another could similarly deliver such prebiotic molecules to baby exoplanets . However, there was no supporting observational data to back up this claim.

A chemical potpourri

To figure out which chemicals 3I/ATLAS contains, astronomers have been recording the comet's light intensity across a range of frequencies, using more than a dozen instruments on Earth and around the solar system. This was possible because the comet spewed tons of gas and dust to create a fuzzy bright halo , or coma, after the sun warmed it. Observations of this coma have turned up an eclectic group of chemicals essential for life as we know it.

One is hydrogen cyanide (HCN), which was detected by the Atacama Large Millimeter/submillimeter Array (ALMA). Despite its notorious reputation as a poisonous gas, HCN is important for creating life. A commentary noted that laboratory experiments dating back to the 1950s ‪—‬ including the famous Miller-Urey experiment , which attempted to recreate the conditions of primordial Earth ‪—‬ have found that HCN is involved in building molecules like amino acids.

The list of ingredients goes on. ALMA data also revealed that 3I/ATLAS released gigantic amounts of formaldehyde and methanol . Additionally, observations from the James Webb Space Telescope showed 3I/ATLAS spewing the greenhouse gas methane . This is important because, assuming the methane formed on planets in the comet's home system, it could have trapped heat on those planets, thus warming them and making them more hospitable to life.

Unlike other interstellar comets, 3I/ATLAS is rich in organic compounds, which NASA's SPHEREx telescope detected in early 2026. (Image credit: NASA/JPL-Caltech) The presence of all these molecules is significant, Cordiner said, because they are "heavily implicated in terrestrial prebiotic chemistry studies as key carbon and nitrogen feedstocks [raw materials] for helping build life's molecular precursors," he said. 3I/ATLAS is proof that these "feedstocks" also exist in pastures far beyond our solar system's fences.

These findings are especially important because astronomers couldn't study the previous two interstellar objects to the same extent, Seligman said. He noted that 1I/'Oumuamua, the first interstellar object ever detected in the solar system, was observable for only a few weeks.

"The second interstellar comet 2I/Borisov was discovered right before COVID, so a lot of observations were canceled because of that," Seligman added. (Cordiner noted that the few observations conducted on 2I/Borisov showed that it, too, appears to contain HCN.) In comparison, researchers had almost a year to study 3I/ATLAS with telescopes. These observations have shown that "3I/ATLAS is unique in terms of the *measured* chemical inventory," Cordiner said.

Not indicative of life

All of the chemicals that 3I/ATLAS appears to possess give us data about just one planetary system. But when combined with observations of other astronomical phenomena, 3I/ATLAS shows that the chemical building blocks of life are abundant across our galaxy. For instance, giant molecular clouds — dense regions of gas and dust that give rise to stars — contain nitriles and sugar acids that can form amino acids. The stuff of life, it seems, is plentiful in space.

James Webb telescope observations showed that 3I/ATLAS has a lot of methane. If its home system's planets contained similar amounts of methane, they may have warmed sufficiently to support liquid water and, possibly, life. (Image credit: NASA, ESA, CSA, STScI, M. Belyakov (Caltech), I. Wong (STScI), Image Processing: A. Pagan (STScI)) Related stories

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Ingredients aside, these findings don't prove that life itself has developed in 3I/ATLAS' home system (or anywhere else). All of the organic molecules that 3I/ATLAS appears to contain have simple chemical structures. Cordiner said mixtures of such molecules in the lab have transformed into more complex ones via processes like ice irradiation . However, such compounds have not been found on 3I/ATLAS, despite the billions of years the comet likely spent exposed to the unabated radiation of interstellar space.

Most of the chemicals 3I/ATLAS released while zipping past the sun come from the comet's radiation-exposed upper layers and not from its pristine interior, a January study found. This would mean that what astronomers have measured may not be present in the comet's home system.

Nonetheless, many astronomers, including Seligman's group, are continuing to study 3I/ATLAS' composition. There is also the exciting possibility of future interstellar visitors, which are all but guaranteed to make an appearance, thanks to the Vera C. Rubin Observatory in Chile , which is expected to spot dozens more. The elements and isotopes found in these objects will help in "building a map of where bio-precursors reside, across the history of the Galaxy," Cordiner said.

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Researchers in Japan have switched on "Shunkai," a neutral atom quantum computer that scientists hope to scale into a 10,000-qubit behemoth by March 2031.

Shunkai is the first full-stack system of its kind in Japan, meaning it features the software, control and hardware layers needed to read user inputs and return a result — not unlike a conventional PC. In theory, that means it should be easier for researchers to get some meaningful use out of the machine, with the team behind Shunkai planning to open it up to external users over the coming years.

In a statement , project lead Kenji Ohmori , a professor of photo-molecular science at the Institute for Molecular Science, said researchers' use of Shunkai would "lead to ripple effects on various fields in industry, academia, and government around the world."

The team behind the new machine plans to integrate it into an existing shared supercomputing facility to create a quantum-GPU hybrid computing center.

Quantum computers: Powerful but impractical

Unlike traditional, or "classical," computers, quantum computers operate according to the strange laws of quantum physics . In quantum systems, qubits — in the form of superconducting circuits, trapped ions or photons (among other modalities) — represent the fundamental building blocks of quantum information. These can exist as a 1, 0, or a " superposition " of both states at once.

However, qubits are notoriously fragile . Even minor environmental interference can destabilize or destroy the information they contain, making accuracy an ongoing challenge in the world of quantum computing. The error rate in qubits is thought to be roughly 1 in 1,000, compared with around 1 per billion or even 1 per trillion operations in classical computing bits.

It's why a huge amount of research is dedicated to quantum error correction . This field seeks to alleviate this inherent unreliability by building redundancies into the way information is encoded in qubits so that small errors don't scrap entire computations.

The broad aim is to create higher-quality qubits and then scale up the number of qubits in a system so quantum computers can finally compete with the world's fastest supercomputers .

This thorny issue, combined with quantum systems' need for elaborate cooling systems to keep them operational , makes them impractical outside of finely tuned lab environments.

A more reliable quantum system?

Shunkai, named after 17th-century Japanese astronomer Harumi Shibukawa , shirks at least some of those constraints. Rather than using supercooled circuitry, Japan's new system incorporates neutral atoms as qubits, captured and suspended using "optical tweezers."

These tightly focused laser beams capture atoms and arrange them inside a vacuum chamber, while microwaves or laser light are used to manipulate the atoms' quantum states and perform calculations. The results are then read by observing the fluorescence from each individual atom with a camera.

Importantly, Shunkai's use of neutral atoms as qubits instead of superconducting circuits means it can operate at room temperature . Because the arrangement of qubits in neutral-atom systems can be fine-tuned during calculations , researchers can also adjust which qubits interact with each other and create entanglement — a bizarre state of information sharing between particles over time and space — between different pairs.

This could help overcome two of the biggest obstacles facing practical quantum systems: scaling machines to large numbers of qubits, and correcting the errors that inevitably creep into quantum calculations.

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To that end, Shunkai will be partially opened to external researchers to develop applications and test and improve the system's quantum error correction capabilities, representatives from Japan's National Institutes of Natural Sciences said in the statement.

The quantum system will initially operate with around 50 qubits before expanding to roughly 500. The longer-term goal is considerably more ambitious: By March 2031, the team aims to scale Shunkai into a "large-scale, high-performance neutral-atom fault-tolerant quantum computer, with 10,000 physical qubits and quantum error detection and correction capabilities." Doing so would place it comfortably above the 6,100-qubit, neutral atom array demonstrated by Caltech researchers in October 2025.

"Neutral atom-based quantum computers have recently been rapidly attracting attention around the world as a new modality that could exceed the limits of the superconducting modality," Ohmori said. "I think it is extremely significant that now we have developed Japan's first full-stack quantum computer in this cutting-edge modality and started its operation."

Can you match these ancient devices to their pictures? Find out with our computing quiz!

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Scientists may have settled a decades-long debate about bat evolution, including controversial questions about when bats began to communicate and fly, a landmark study shows.

The new research, published Wednesday (Sept. 23) in the journal Nature , is the biggest bat DNA and fossil study ever conducted. Researchers created new, top-quality genome assemblies for 41 bat species, which they analyzed together with 62 existing sequences, providing a record dataset of 103 bat genomes and 44 bat fossils.

"It is extraordinary," study co-author Emma Teeling , a professor of molecular evolution and mammalian phylogenetics at University College Dublin, told Live Science in an email; "after decades of research and conflicting findings, we finally have uncovered how and when bats evolved."

The analysis suggests that bats arose in Europe around 65 million years ago, contradicting previous hypotheses proposing Asian , African or North American origins around 50 million years ago. Additionally, the researchers found that echolocation and true flight evolved early in bats, roughly 50 million years ago, rather than multiple times after modern bats began to diversify.

"This study transforms bat evolution research because it finally gives us a robust, resolved family tree and biogeography, something that's eluded scientists for decades," study co-author Sonja Vernes , a professor and head of the Neurogenetics of Vocal Communication Research Group at the University of St Andrews in the U.K., told Live Science in an email. "Get the tree right, and everything else about bat evolution starts to fall into place."

The study included members of all 21 recognized bat families, as well as some of the most remarkable bat species known on Earth. For example, the dataset contained the bumblebee bat ( Craseonycteris thonglongyai , also called the Kitti's hog-nosed bat), which, at about 1 inch, or 2.5 centimeters, long, is thought to be the smallest mammal on Earth; and the Madagascar's sucker-footed bat ( Myzopoda aurita ), which has suction cups on its wrists and ankles to help it cling to smooth surfaces.

The research team — which comprised 137 scientists affiliated with Bat1K , an international project to map the genomes of all living bat species — used advanced DNA sequencing and computational techniques to identify individual genes and redraw the bat family tree.

"The value we bring is in innovative methods and unparalleled data that together yield an evolutionary tree that includes all these key fossils," study co-author Liliana Dávalos , a professor of phylogenetics and tropical deforestation at Stony Brook University in New York, told Live Science in an email.

Among other discoveries, the researchers found that a 50 million-year-old fossil from southern France of the extinct species Vielasia sigei , which shows signs of advanced echolocation , sits within the oldest branch of the bat family tree, indicating that echolocation predates the diversification of modern bats. This finding, together with the result that true flight appeared early in bats, helps to explain why this lineage has been so successful and evolved into more than 1,500 species worldwide today, according to the study.

With a body length of about 1 inch, the bumblebee bat ( Craseonycteris thonglongyai ) is thought to be the smallest mammal on Earth. It occurs in western Thailand and southeast Myanmar. (Image credit: Daniel Whitby) After emerging in Europe, bats quickly dispersed into Africa, establishing a Europe-Africa hub from which they expanded into Asia, the Americas and Australia, the results suggest. Bats are the only mammals capable of true flight, meaning they flap their wings and don't simply glide or parachute. Throughout their evolution, they have acquired longer lifespans than other mammals of similar body size, surviving eight to 10 times longer than might be expected and showing few signs of aging and cancer, according to the study.

"Some bat species live remarkably long lives for their size, and can shrug off diseases that would make us seriously ill," Vernes said. "Until now, we didn't have a solid enough foundation to properly understand how bats evolved their most extraordinary traits, from flight and echolocation to their remarkable lifespans and resistance to disease. Now we do."

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The genomic resource built for the study lays the foundation for future research into bats' longevity and disease resistance, with potential benefits for humans, Vernes said. "If we can understand how they do this at the genetic level, it could eventually help us design bat-inspired approaches to improve human health," she said.

The findings could also aid bat conservation through genomic methods. Protecting bats is important because they help to maintain healthy ecosystems by pollinating plants, dispersing seeds and consuming huge numbers of insect pests, Vernes said. There is also more work to be done to identify the ancestor of all living bats, whose genome the researchers took a first stab reconstructing.

"For me, this isn't the end of the story," Vernes said; "it's just the first chapter."

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Earth's continents are losing fresh water much faster than scientists thought, mostly because aquifer pumping in regions like northern India, southern Iran and parts of the U.S. is 45% more pronounced, on average, than previous estimates suggested, new research shows.

The study used satellite data to map freshwater trends across the globe between 2002 and 2025. Thanks to a high-resolution rendering method, researchers revealed regional gains and reductions in terrestrial water storage that were 33% more marked, on average, than in previous studies. The amount of fresh water lost was much higher than the gains overall, highlighting the urgent need for better water management to stave off a global water crisis.

"It has become very dire in a lot of places," Hrishikesh Chandanpurkar , a hydrologist and the co-founder of the nonprofit Evergreen Resilience Institute, who was not involved in the study, told Live Science.

Researchers created a map of terrestrial freshwater trends from 2002 to 2025. They then attributed these trends to human and climate drivers. (Image credit: O'Neill, Rodell and Loomis, 2026. PNAS . (CC BY 4.0) .) The study also attributed the changes in freshwater storage to different human and climate drivers, said first author Mary Michael Forrester O'Neill , a researcher at the University of Maryland's Earth System Science Interdisciplinary Center and the Hydrological Sciences Laboratory at NASA's Goddard Space Flight Center.

"Earlier studies could see broad patterns of long-term freshwater loss or gain but couldn't reliably tell how much was due to human activity versus climate swings, in part due to resolution limitations," Forrester O'Neill told Live Science in an email. "This study sharpened the picture and used geostatistical methods to rank the impacts of human causes, like irrigation and dam building, against climate factors, like rainfall and drought."

The researchers found 94 regions with above-background shifts in freshwater storage, 40 of which were influenced mainly by human land or water use, rather than climate variability and global warming . The team then focused on these 40 hotspots to pinpoint exactly where people can act to conserve water.

"Water managers and downstream communities need to know which aquifer, reservoir, or irrigation district is responsible for a given trend in large-scale freshwater storage, not just that 'somewhere in this country, water is being lost,'" Forrester O'Neill explained.

Freshwater gains in 22 regions were due to rain-fed agriculture, irrigation with surface water, reservoir impoundment and deforestation, which decreases evapotranspiration and plants' groundwater consumption, according to the study. In contrast, freshwater losses in the remaining 18 hotspots were caused by irrigation with groundwater and the construction of canals, diversions and other water infrastructure.

The findings, published Sept. 14 in the journal PNAS , show that human water use is a significant driver of water storage changes on every continent except Australia and Antarctica , where climate factors are more influential, O'Neill said. Local freshwater gains and losses may cut freshwater availability downstream or in the surrounding region, she and her colleagues noted in the study.

One example of a region that gained fresh water in the study is the area of central Russia that hosts the Boguchany Reservoir, a giant artificial lake that was filled in 2012 after the construction of a hydroelectric dam. And three stark examples of places that lost fresh water are northern India, southern Iran and the southern High Plains (a region at the intersection of Colorado, Kansas, New Mexico, Oklahoma and Texas), because these regions host major breadbaskets that tap aquifers for irrigation, O'Neill said.

The results are concerning because the places with the worst groundwater depletion overlap with areas that irrigate crops unsustainably, O'Neill said. Previous research shows that critical food-producing regions ‪—‬ such as the U.S. High Plains, California's Central Valley, northern India, Pakistan, North China and the Fertile Crescent ‪—‬ consistently overuse groundwater. "Within these regions, we found the pace of depletion is considerably more severe than earlier estimates suggested, reinforcing food security concerns," she said.

One of the novelties of the paper is its very high resolution, said Chandanpurkar, who last year led a study describing "mega-drying" regions across the world and co-authored a report on continental drying . The new study used data from NASA's Gravity Recovery and Climate Experiment (GRACE) mission and its Follow-On successor (GRACE-FO), which have measured subtle redistributions of mass on Earth. But unlike previous studies, the new research resolved the data in high resolution, he said, like correcting blurry vision with glasses.

"This is not a brand-new method, but it's the first time they're applying it to these regional hotspots and then trying to figure out what they mean," Chandanpurkar said.

The new study (A) produced a much sharper picture of freshwater trends than standard processing methods and previous studies did (B). (Image credit: O'Neill, Rodell and Loomis, 2026. PNAS . (CC BY 4.0) .) Scientists already knew that groundwater depletion and other human water uses are "quite staggering," and this study is a reminder that continental drying is "a very big deal," Chandanpurkar said. "Water is really undervalued," he said. "Giving it its proper dues would be essential for this [freshwater loss] to really be acknowledged by leaders and economists."

It's impossible to say exactly how many years or decades humans can go on consuming this much fresh water before it runs out , partly because the climate can be unpredictable and partly because it's hard to tell how much water remains in Earth's reservoirs, Forrester O'Neill said.

"GRACE satellites measure the rate of change in water mass, not the total volume stored in an aquifer, so we have no independent basis for estimating time to depletion or a timeline for systems to collapse," she said.

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However, there will come a point when the cost of pumping groundwater, for example, will be too high to pay in some regions. Water table declines of just a dozen feet (a few meters) or so can cause a substantial share of wells to run dry, research shows , and the expense of drilling deeper will affect at-risk communities most of all, Forrester O'Neill said.

"We are most concerned about the rising cost and inequity of continuing to reach water that keeps retreating deeper underground, paired with strain on existing surface water resources," she said. "Of course, water-scarce regions exhibiting acute groundwater depletion are at risk, like Iran , Saudi Arabia, Syria, Türkiye, Iraq, and Libya. Another one to keep an eye on would be Mexico , simply because of the documented, progressively increasing well depth paired with the observed terrestrial water storage loss."

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Google DeepMind has revealed a new artificial intelligence (AI) tool that can predict the molecular impacts of tweaking any one of the billions of letters that make up our genetic code.

On Sept. 8, Google's AI powerhouse announced a freely available database called AlphaGenome Atlas , which contains data on 9 billion possible changes to the human genetic code and estimates how these changes will affect different tissues and cellular processes. What's more, the tool spits out a simple score to help scientists quickly weigh the knock-on impacts of these changes.

How a sequence of 3 billion or so letters of chemical code is packaged, delivered and read to create a human life is a major question in genetics research. Last year, DeepMind announced a tool that could propel researchers toward an answer. The tool, called AlphaGenome , predicts how changes to a DNA sequence alter proteins, cells and, ultimately, the human experience.

Now, one year later, DeepMind has released AlphaGenome Atlas, which the tech giant hopes will make AlphaGenome accessible to more researchers.

"It looks like a great resource," Greg Findlay , a group leader at the Francis Crick Institute in London who isn't involved with AlphaGenome Atlas, told Live Science. However, other experts said that, although the tool is a step forward, it still can't answer all of the big questions in genetics .

"It's not this holy grail," Tuuli Lappalainen , a professor in genomics at KTH Royal Institute of Technology in Stockholm and a senior associate faculty member at the New York Genome Center who isn’t involved with AlphaGenome Atlas, told Live Science.

Reading the future of genetic variants

Lappalainen's lab has been using AlphaGenome to study the effects of variation in genomes over the past year. She pointed out that this technology is not new. However, according to Google DeepMind, AlphaGenome outperforms previous models in the resolution at which it can predict the impact of changes to the genome. Around 98% of our DNA is noncoding , meaning cellular machinery doesn't directly read it to make the proteins that keep our cells functioning.

Geneticists now appreciate that this code, once thought to be "junk" DNA, is instead needed to manage how and when to read the parts of the genome that do encode our molecular building blocks, or coding genes. However, evolution hasn't produced an ordered genome. Instead, some regulatory instructions are distributed widely throughout the code.

AlphaGenome allowed researchers to explore how changes in a single pair of DNA "letters" could influence up to 1 million pairs of surrounding code ‪—‬ a far greater spread than previous models were capable of and one that captured much of each gene's regulatory network.

You really do not need to be an expert in these methods to be able to go there and look something up in a browser.

Tuuli Lappalainen, professor in genomics at KTH Royal Institute of Technology and a senior associate faculty member at the New York Genome Center

But this power came at a price. Until the release of Atlas, AlphaGenome required users to have enough bioinformatics experience to access and use the models' automated programming interface ‪—‬ an area of expertise not all geneticists have. What's more, calculating the effects of each change was a strenuous workout for academics’ computing resources.

To create AlphaGenome Atlas, DeepMind researchers computed every possible base ("letter") change and made the resulting data ‪—‬ totaling 1 petabyte, or 1 million gigabytes, of information ‪—‬ freely available. This takes the load off academics' overworked personal computers. What's more, the technology is now wrapped up in an easy-to-access, user-friendly web portal.

"You really do not need to be an expert in these methods to be able to go there and look something up in a browser," Lappalainen said.

Another simplification is the AlphaGenome Variant Impact score, a metric that predicts how much biological effect a change will have. In an accompanying preprint paper , DeepMind showed that the score could separate disease-linked mutations from harmless ones in a clinical dataset. While the score's simplicity might make it harder to interpret in certain cases, Lappalainen said, it would be useful for researchers who want to investigate a list of gene variants.

Clouds in the crystal ball?

The tool still isn't a perfect predictor, however. A Sept. 11 preprint study from a research team led by Katie Pollard , director of the Gladstone Institute of Data Science and Biotechnology and a professor at the University of California, San Francisco, suggested that while AlphaGenome was adept at finding causal mutations, it persistently underestimated their impact.

Pollard's team found that the model couldn't always link changes in regulatory elements to the genes they controlled, especially when they were not close together on the genome. "My perhaps naive hope would be that people take these predictions with an appropriate grain of salt," Lappalainen said.

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Despite these limitations, Lappalainen said advances like AlphaGenome Atlas are part of a wider move toward more collaborative, data-led genomics. But she warned that the field would need to give equal focus to "wet-lab" experiments, which work out the accuracy of variant predictions.

Although these tests are tedious and consume much more time than a search on AlphaGenome Atlas' interface, she said, they are essential for generating the data that AI models need to improve their predictions.

"We're still very much data-limited in biology, and that data needs to be created," Lappalainen said.