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Scientists discover blood signal that may detect ovarian cancer in early stage
Researchers from Hoag Family Cancer Institute in Newport Beach, California described in Nature Medicine an RNA molecule called Tu-Stroma, whose elevated blood level indicates precancerous changes in fallopian tubes (STIC). In the study, the test detected STIC in 92.3% of sick women and correctly identified 98.2% of healthy ones. In women with genetic risk of ovarian cancer, a negative result would be correct in nearly 100% of cases. The discovery may help avoid preventive surgery to remove fallopian tubes and ovaries in patients who do not actually have precancerous changes.
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