CRISPR therapy CTX310 reduces bad cholesterol by over half in single treatment

A Cleveland Clinic study published in "New England Journal of Medicine" shows that experimental gene therapy CTX310 reduces LDL levels by over 50% after a single treatment, with effects lasting one year. The method is based on CRISPR technology and blocks production of the ANGPTL3 protein, mimicking a rare natural genetic variant that protects against atherosclerosis. High LDL levels promote plaque accumulation in arteries and increase the risk of heart attack and stroke.

Similar stories

🔬 Science CRISPR allows attacking blood cancer without destroying healthy cells Science Daily · 1d ago 🏥 Health Single gene-editing treatment slashed LDL cholesterol for a full year in small study NYT Health · 29d ago 🔬 Science Anthropic AI lab discovers DNA sequences in viruses similar to CRISPR Nature · 1d ago